The natural way to control acne: postbiotics to modulate the growth of Cutibacterium acnes
NB-CutiBalance is the first cosmetic bioactive that has demonstrated its effectiveness in regulating the overgrowth of Cutibacterium acnes associated with acne lesions, returning its levels to those existing in healthy skin, thus preserving its positive biological functionality without generating acne.
Treat acne with microbial biotherapy
Cutibacterium acnes (formerly Propionibacterium acnes) is a bacillus that is part of the normal microbiota of the skin, found mainly in the fattier parts of the body where it feeds on fatty acids secreted by the sebaceous glands. Various studies have found a close relationship between the overgrowth of Cutibacterium acnes and the development of various infections such as acne, endocarditis and post-surgical infections. However, it has been observed that this bacteria has functions in maintaining skin homeostasis and preventing pathogen colonization.
Demonstrated efficacy
In vitro study
In vitro study performed with Cutibacterium acnes strain CECT 5684 isolated from an acne lesion. 2% erythromycin is the antibiotic of choice for topical treatment of acne.
Clinical studio
Clinical study performed with 22 volunteers with different types of acne. NB-Cutibalance was used at 6% conetration in a gel, two applications per day during 28 days.
Volunteer 6 / Acne grade 2
Before the treatment D0 / After the treatment D28
Volunteer 21 / Acne grade 3
Before the treatment D0 / After the treatment D28
Volunteer 15 / Acne grade 4
Before the treatment D0 / After the treatment D28
El acné
El 85% de los adolescentes lo padecen en distintos niveles de gravedad.
Casi un 20% de los adultos también lo presenta, sobretodo mujeres.
Es una de las 10 alteraciones cutáneas de mayor prevalencia en el mundo.
Los productos para el acné es la categoría de cosméticos más vendida en menores de 30 años.
Product specifications
INCI: Bifidobacterium/Cysteine HCl Ferment Extract Filtrate/ Bifida ferment extract; benzyl alcohol, dehydroacetic acid,benzoic acid, sorbic acid.
Specifications:
- Appearance: Liquid
- Color: Amber
- Olor: specific
- pH: 3,4 – 4,7
- Solubility: Water
Expiration:
- 18 months
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