The natural way to control acne: postbiotics to modulate the growth of Cutibacterium acnes

NB-CutiBalance is the first cosmetic bioactive that has demonstrated its effectiveness in regulating the overgrowth of Cutibacterium acnes associated with acne lesions, returning its levels to those existing in healthy skin, thus preserving its positive biological functionality without generating acne.

Treat acne with microbial biotherapy

Cutibacterium acnes (formerly Propionibacterium acnes) is a bacillus that is part of the normal microbiota of the skin, found mainly in the fattier parts of the body where it feeds on fatty acids secreted by the sebaceous glands. Various studies have found a close relationship between the overgrowth of Cutibacterium acnes and the development of various infections such as acne, endocarditis and post-surgical infections. However, it has been observed that this bacteria has functions in maintaining skin homeostasis and preventing pathogen colonization.

ExtraBiotics-nb-cutibalance-acne

Demonstrated efficacy

In vitro study

In vitro study performed with Cutibacterium acnes strain CECT 5684 isolated from an acne lesion. 2% erythromycin is the antibiotic of choice for topical treatment of acne.

Clinical studio

Clinical study performed with 22 volunteers with different types of acne. NB-Cutibalance was used at 6% conetration in a gel, two applications per day during 28 days.

extrabiotics-estudio-clinico.paciente6-antesextrabiotics-estudio-clinico.paciente6-despues

Volunteer 6 / Acne grade 2

Before the treatment D0 / After the treatment D28

Volunteer 21 / Acne grade 3

Before the treatment D0 / After the treatment D28

Volunteer 15 / Acne grade 4

Before the treatment D0 / After the treatment D28

The Acné

85%

85% of adolescents suffer from it to varying degrees of severity.

20%

Almost 20% of adults also have it, especially women.

1/10

It is one of the 10 most prevalent skin disorders in the world.

>30

Acne products are the best-selling cosmetics category for people under 30.

Product specifications

INCI: Bifidobacterium/Cysteine HCl Ferment Extract Filtrate/ Bifida ferment extract; benzyl alcohol, dehydroacetic acid,benzoic acid, sorbic acid.

Specifications:
- Appearance: Liquid
- Color: Amber
- Olor: specific
- pH: 3,4 – 4,7
- Solubility: Water

Expiration:
- 18 months